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Team finds compounds that strongly curb ALS neuron death

  • May 25, 2017
  • , Jiji Press , 3:00 a.m.
  • English Press

Kyoto, May 25 (Jiji Press) — A Kyoto University-led team has announced that they identified compounds that strongly curb the death of motor neurons generated from induced pluripotent stem, or iPS, cells of amyotrophic lateral sclerosis patients.

“We can’t use them to treat patients immediately, but our finding is expected to contribute to research and development for new drugs,” the team said on Wednesday.

The team included Prof. Haruhisa Inoue of the Kyoto University Center for iPS Cell Research and Application, known as CiRA.

In ALS, motor neurons, which pass instructions from the brain to the muscles, degenerate and die. As the disease progresses, sufferers lose their ability to move their muscles.

The cause and development of the fatal disease are not clearly understood. There is no established cure.

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