Yokohama City University Associate Professor Takanori Takabe, Professor Hideki Taniguchi, and several other researchers have developed a strategy for mass-producing “micro livers,” small tissues capable of functioning as human livers, from human induced pluripotent stem cells (iPS). The technique makes it possible to produce about 20,000 micro livers, more than 100 times the conventional method, in one cell plate. This may help realize regenerative medicine via the transplantation of micro livers to patients suffering from liver failure.
The method was co-developed by biotechnology venture firm Healios, Kuraray, Ajinomoto, and several other organizations. The findings will be published in Cell Reports, an American scientific journal, on Dec. 6. (Abridged)